Morphine Sulfate
Morphine sulfate is a highly potent opioid analgesic. It acts directly on the central nervous system to relieve severe pain. Due to severe risks of addiction, abuse, misuse, and life-threatening respiratory depression, it is classified as a Schedule II controlled substance.
Dosage by Body Weight
Dosages must be highly individualized. For pediatric patients, dosing is strictly based on weight (typically 0.15 to 0.3 mg/kg orally or 0.05 to 0.1 mg/kg intravenously/intramuscularly) and must be calculated and administered by a qualified healthcare provider. Do not use without professional medical supervision.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Neonates are highly sensitive to respiratory depression. Use with extreme caution under specialized specialist supervision.
- Body Weight
- 5-7 kg
- Dose
- 0.5 mg to 1.4 mg (oral equivalent)
- Frequency
- Every 4 hours as needed
- Tracking Notes
- Calculated based on standard pediatric dosing of 0.1 to 0.2 mg/kg. Monitor vital signs closely.
- Body Weight
- 8-10 kg
- Dose
- 0.8 mg to 2.0 mg (oral equivalent)
- Frequency
- Every 4 hours as needed
- Tracking Notes
- Ensure exact concentration of liquid formulation is used to prevent accidental overdose.
- Body Weight
- 11-15 kg
- Dose
- 1.1 mg to 3.0 mg (oral equivalent)
- Frequency
- Every 4 to 6 hours as needed
- Tracking Notes
- Only use pediatric-specific oral solutions. Keep out of reach of children.
- Body Weight
- 16-20 kg
- Dose
- 1.6 mg to 4.0 mg (oral equivalent)
- Frequency
- Every 4 to 6 hours as needed
- Tracking Notes
- Monitor for side effects such as severe drowsiness, constipation, or shallow breathing.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Neonates are highly sensitive to respiratory depression. Use with extreme caution under specialized specialist supervision. |
| 5-7 kg | 0.5 mg to 1.4 mg (oral equivalent) | Every 4 hours as needed | Calculated based on standard pediatric dosing of 0.1 to 0.2 mg/kg. Monitor vital signs closely. |
| 8-10 kg | 0.8 mg to 2.0 mg (oral equivalent) | Every 4 hours as needed | Ensure exact concentration of liquid formulation is used to prevent accidental overdose. |
| 11-15 kg | 1.1 mg to 3.0 mg (oral equivalent) | Every 4 to 6 hours as needed | Only use pediatric-specific oral solutions. Keep out of reach of children. |
| 16-20 kg | 1.6 mg to 4.0 mg (oral equivalent) | Every 4 to 6 hours as needed | Monitor for side effects such as severe drowsiness, constipation, or shallow breathing. |
Formulation
Purpose
Morphine sulfate is used to manage severe acute or chronic pain that cannot be controlled by other alternative pain medications.
Generic Name
Morphine SulfateBranded Drug Names
Morphine Sulfate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.